EP-HGA.ES-4C100 — 4 Cavities Medicine Bottle Blow Molding Machine
De EP-HGA.ES-4C100 Medicine Bottle Blow Molding Machine is a high-efficiency, 4-cavity system engineered for precision pharmaceutical and cosmetic packaging. Capable of producing containers up to 800ml with a maximum diameter of 80mm and height of 250mm, this machine delivers a theoretical output of 4,600 bottles per hour. It features a clamping stroke of 128mm and a mold-open distance of 323mm, ensuring smooth operation for small-tooth mouth bottles like eye drops. Powered by a 62.5kW heating system and operating at 7 kg/cm² pressure, it integrates advanced pneumatic controls for consistent wall thickness. With a compact footprint of 4170×1930×2340mm and a weight of 4,000kg, the HGA.ES-4C100 combines robust durability with energy efficiency, making it ideal for high-volume medical bottle manufacturing.
EP-HGA.ES-4C100 — 4 Cavities Medicine Bottle Blow Molding Machine
A high-output four-cavity blow molding machine purpose-designed for pharmaceutical and healthcare producers that need both volume and format flexibility. The HGA.ES-4C100 delivers 4,600 bottles per hour across four simultaneous blow cavities, handling containers up to 800 ml with neck diameters up to 68 mm. Built on the proven two stage blow molding machine platform, it combines pharmaceutical-grade process control, servo-electric actuation, and independently zoned infrared heating to produce consistently dimensioned bottles across long production runs — a specification level that regulated markets in Colombia, Australia, South Korea, and the Netherlands increasingly require from their bottle blow molding machine suppliers.
Technical Specifications — HGA.ES-4C100 Blow Molding Machine
All performance data applies to the HGA.ES-4C100 four-cavity model tested under standard conditions with PET resin at nominal process settings.
| Category | Parameter | Eenheid | Waarde |
|---|---|---|---|
| Molding | Clamping Stroke | mm | 128 |
| Mold-Open Distance | mm | 328 | |
| Mold-Close Distance | mm | 200 | |
| Stretching Stroke | mm | 350 | |
| Preform Mold-Open Distance | mm | 50 | |
| Bottle Mold-Close Distance | mm | 100 | |
| Preform Holder / Cavities | — | 92 / 4 | |
| Container | Maximale containerinhoud | ml | 800 |
| Max. Neck Diameter | mm | 68 | |
| Max. Container Diameter | mm | 80 | |
| Max. Container Height | mm | 250 | |
| Output | Theoretical Output | bph | 4,600 |
| Electrical System | Max. Heating Power | kW | 62.5 |
| Steady Heating Power | kW | 21 | |
| Air System | Operating Pressure | kg/cm² | 7 |
| Low Pressure Air Consumption | ltr/min | 800 | |
| Blowing Pressure / High Pressure Air | kg/cm² / ltr/min | 35 / 4,000 | |
| Cooling Water | Operating Pressure | kg/cm² | 5–6 |
| Temperature | °C | 8–12 | |
| Flow Rate | ltr/min | 30 | |
| Machine | Afmetingen van de machine (L×B×H) | mm | 4170 × 1930 × 2340 |
| Machinegewicht | kg | 4,000 |
Medicine Bottle Blow Molding Machine
Key Advantages of This Blow Molding Machine
4,600 bph with Four-Cavity Precision
At 4,600 bottles per hour, the ES-4C100 is one of the highest-output units in the Medicine Bottle Series that still maintains the per-bottle dimensional accuracy pharmaceutical producers require. Each of the four cavities operates with matched tooling and synchronized clamp timing, so variation between cavities — the most common source of batch rejection in multi-cavity bottle blow molding machine designs — is minimized from the first production cycle.
68mm Neck Diameter for Wide-Format Pharmaceuticals
The 68 mm neck diameter ceiling and 80 mm maximum body diameter expand the container range of this automatic pet blowing machine beyond what narrow-neck pharmaceutical machines support. Wide-mouth supplement jars, multi-dose powder containers, and large-format liquid medicine bottles all fall within the tooling envelope — giving pharmaceutical contract manufacturers a single blow molding machine that covers formats from compact syrup bottles to bulk supplement containers.
Energy-Efficient Servo-Electric Drive
The 62.5 kW installed heating capacity steps down to a steady-state draw of just 21 kW once oven zones stabilize — a 66% reduction from peak that reflects the servo-electric philosophy of the ES series. No hydraulic pump runs at constant load; actuators draw power only when moving. Over a 6,000-hour annual production schedule, this characteristic saves a measurable amount of industrial electricity versus a hydraulic equivalent — a factor increasingly important to pharmaceutical producers managing energy costs in Colombia, Australia, and South Korea.
350mm Stretch for Optimal PET Orientation
The 350 mm stretching stroke delivers the axial extension ratio required for full biaxial orientation of PET and PETG in 500–800 ml pharmaceutical containers. Correct orientation is not a cosmetic feature — it determines the drop resistance, top-load strength, and oxygen and moisture barrier performance of the finished container. These are the properties measured during packaging qualification for regulated pharmaceutical products in markets including Colombia, the EU, and Australia, and getting them right starts with matching the stretch stroke to the bottle geometry.
HMI Recipe Management for Fast Format Changes
All process parameters for every bottle format the machine has been qualified on are stored as named recipes accessible from the HMI touch panel. Recalling a recipe restores all seven oven zone setpoints, stretch rod speed, blowing pressure ramp, cooling time, and clamp sequence timing simultaneously — reducing the operator intervention required during a format change to tooling swap plus recipe recall, rather than the full parameter re-entry that was standard practice on older plastic blow molding machine ontwerpen.
Patent-Protected Neck Finish Engineering
The preform injection tooling on this two stage blow molding machine incorporates neck-finish geometry covered by registered national patents developed over more than 20 years of pharmaceutical packaging R&D. The tooling ensures that gate vestige and parting line positions on the finished bottle do not interfere with sealing face contact or child-resistant closure engagement — two performance criteria assessed during packaging qualification in regulated pharmaceutical markets worldwide.
Partner Brands
Over two decades of focused blow molding machine development have produced an engineering capability and a client portfolio that covers the most demanding segments of pharmaceutical and consumer goods packaging. Our multi-resin platform — supporting PET, PETG, PC, PCTG, and PP — and our continuous patent investment have earned the trust of brand owners including Yibao, Haitian, Luhua, Walch, Blue Moon, Proya, Libai, Estée Lauder, Walmart, Da Senlin, and Shining Eye Drops. We continue to improve every generation of blow molding machine we produce based on production data and client feedback from facilities across five continents.
Blow Molding Machine's Mold System Overview
The four-cavity ES-4C100 separates preform and bottle tooling into two independent stations — a structural requirement of all two step blow molding platforms and a significant maintenance advantage over single-stage systems. Each station can be removed, inspected, and re-qualified independently without taking the whole machine offline. This is particularly valuable for pharmaceutical facilities running under GMP where a tooling maintenance event must be documented separately from a production batch record, and where the ability to pre-qualify replacement tooling before swapping it into production minimizes downtime impact on batch scheduling.
Preform Injection Mold
- The split die-lip construction maintains preform coaxiality throughout the injection cycle, preventing the offset wall thickness that causes asymmetric blowing and container lean in the finished bottle.
- Cooling circuits are routed to maximize heat extraction rate from each preform position, supporting the 4,600 bph cycle rate without pushing preform crystallinity beyond the process window for effective biaxial stretch-blow of pharmaceutical containers.
- Cavity-forming surfaces are machined from imported 2316 die steel, which combines rust resistance with sustained hardness under the injection pressures required for thick-walled pharmaceutical preform designs.
- Core plates and cavity plates are fabricated from 420 stainless steel for chemical resistance against pharmaceutical-grade cleaning and sanitizing agents that are standard in GMP production areas.
- Tooling components follow standardized interchangeable specifications across the HGA.ES series, allowing spare parts inventory to be shared across multiple machines and machine generations within the same facility.
- A single preform mold base can be configured to produce more than one preform geometry, which reduces tooling investment when a pharmaceutical packer adds a new bottle format within the existing neck finish range.
Blowing Mold
- Blow cavities are machined from premium hardened tool steel selected for the surface hardness and wear resistance needed for sustained high-volume pet blow molding production across multi-shift pharmaceutical packaging operations.
- Container geometry is developed entirely in 3D CAD before any steel is cut, with stretch ratio simulation used to verify that the blow mold cavity produces the biaxial orientation profile specified in the container qualification document.
- A standard library of pharmaceutical bottle profiles is available for rapid tooling production, with custom geometries developed from the customer's container drawing in the tooling design phase.
- Water cooling channels are routed to follow the outer bottle contour from shoulder to base, removing heat evenly from the blown bottle surface and preventing the post-mold deformation that affects large-format containers without adequate cavity cooling.
- All structural mold components pass through CNC machining centers to maintain the positional tolerances on parting lines, vent positions, and blow-pin alignment that four-cavity synchronous operation requires at 4,600 bph.
Machine Architecture & Control System
The HGA.ES-4C100 is built on a heavy-plate welded steel frame with a machine footprint of 4,170 × 1,930 × 2,340 mm — the largest machine in the four-cavity class within the HGA.ES series. The extended length compared with three-cavity models reflects the longer preform carousel path required to carry 92 preform holders through the injection, oven, and blowing sequence at 4,600 bph. Frame rigidity across this length is maintained by precision-bored guide column sets at both the injection and blowing ends of the machine, ensuring that clamping force distribution across all four blow cavities remains uniform regardless of mold temperature variation during long production runs.
The infrared oven section uses seven independently controlled lamp zones arranged circumferentially around the preform path. For wider pharmaceutical preforms targeting 68 mm neck diameters and 80 mm body diameters, the oven profile must manage a larger thermal mass than narrow-neck configurations — the independent zone control system addresses this by allowing each zone to compensate for the different absorption characteristics of the preform shoulder, body, and base regions. This zone independence is a hallmark of the two stage blow molding machine approach and is why pharmaceutical producers consistently report tighter wall-thickness uniformity from ES-series machines compared with single-stage alternatives when processing large-format pharmaceutical containers.
Servo-electric actuators govern the clamping, carousel indexing, and stretch rod at every station. The stretch rod reaches its 350 mm maximum travel under servo position control coordinated with the high-pressure blowing air valve — a timing relationship managed by the PLC to within a few milliseconds per cycle. At 4,600 bph this coordination must be maintained across millions of cycles without drift, which is why the servo encoder feedback loop and PLC closed-loop control are preferable to the open-loop pneumatic and cam-driven mechanisms used in legacy machine blow designs from earlier generations of pharmaceutical packaging equipment.
How to Select the Right Blow Molding Machine for High-Output Pharmaceutical Bottle Production
Matching a blow molding machine to a pharmaceutical bottle project is fundamentally a question of aligning container geometry, resin type, output requirement, and regulatory context. The HGA.ES-4C100 is the recommended starting point when all of the following conditions describe your production scenario.
Output Above 4,000 bph
You need output above what a three-cavity unit can deliver, but a six-cavity machine would bring excess capacity that your current product portfolio cannot fill economically.
Container Volume 50–800 ml
The four-cavity tooling and 100 mm bottle mold-close distance cover this range with a single machine frame, accommodating both compact syrup bottles and larger pharmaceutical jars in one asset.
Neck Diameter up to 68 mm
The 68 mm ceiling covers most wide-mouth pharmaceutical formats. If your container requires a neck larger than 68 mm, the HGA.ES-2C114.3 with its 88 mm capability is the appropriate next step.
Multi-Format Production
You produce several pharmaceutical bottle SKUs on the same line. HMI recipe management and standardized tooling changeover make the ES-4C100 an efficient multi-format asset compared with dedicated single-format machines.
GMP Regulatory Environment
Your facility is regulated by FDA, EMA, INVIMA (Colombia), TGA (Australia), or MFDS (South Korea) and requires IQ/OQ documentation, material certifications, and CE-compliant electrical design.
Two-Stage vs Single-Stage
When wall-thickness uniformity, neck-finish dimensional accuracy, and biaxial orientation levels are specified in your container qualification document, the two stage blow molding machine route is the only reliable path to consistent compliance at 4,600 bph.
If your required output significantly exceeds 4,600 bph, the HGA.ES-6C76 Blow Molding Machine with its 7,200 bph rating should be evaluated. For volumes above 800 ml at this output level, a custom configuration consultation with our application engineering team is recommended.
Application Scenarios of Blow Molding Machine
The combination of 4,600 bph output, 68 mm neck capability, and 800 ml volume ceiling makes the HGA.ES-4C100 one of the most broadly applicable blow molding machine options in the pharmaceutical and healthcare packaging market. Below are the primary end-market applications where this machine delivers a clear production advantage.
Large Pharmaceutical Tablet & Capsule Jars
Wide-mouth tablet and capsule containers up to 800 ml at neck diameters up to 68 mm represent the primary target for this pet blow molding machine. The combination of volume and neck diameter covers the standard product range for OTC vitamin and supplement brands in Colombia, South Korea, Brazil, and European markets, where large family-size containers with child-resistant closures are the dominant retail format.
Liquid Medicine & Oral Suspension Bottles
The 350 mm stretching stroke produces the biaxial orientation in PET that delivers the drop resistance and chemical resistance required for liquid pharmaceutical containers. Syrup, oral suspension, and pediatric liquid dosage formats across the 100–500 ml range run efficiently on this auto pet blowing machine at the full 4,600 bph rate, which matches the output requirements of most pharmaceutical filling lines in high-volume liquid medicine production.
Nutraceutical & Sports Nutrition Containers
Premium protein powder tubs and bulk vitamin capsule containers in the 500–800 ml range with wide-mouth neck finishes are a growing production requirement for contract packaging organizations across South Korea and Australia. The four-cavity output and PETG resin capability of this blowing molding machine match both the production volume and the surface quality that premium nutraceutical brands require for shelf differentiation in competitive health retail environments.
Cosmetic & Premium Personal Care
Body lotion, hair care, and skin treatment packaging in the 200–500 ml range with neck diameters between 24 mm and 68 mm can be produced at cosmetics-industry surface gloss on this plastic blow molding machine using PETG resin. The four-cavity output makes it economical for cosmetic brands that operate at the mid-volume scale where dedicated cosmetics-only packaging lines become justified by annual volume.
Medical Device & Diagnostic Packaging
PC and PCTG containers for medical device components, diagnostic reagents, and sample collection kits require the combination of optical clarity, impact resistance, and dimensional accuracy that injection blow molding provides. The ES-4C100 produces these containers to the tolerances medical device packaging specifications require, with the material certifications needed for submission to regulatory bodies including INVIMA in Colombia and TGA in Australia.
Food Supplement & Functional Beverage
Health drink brands and food supplement producers increasingly specify spuitrekblaasvormmachine quality for their PET containers — clear, glossy, dimensionally tight containers that communicate premium quality on retail shelves. At 4,600 bph this blow molding machine can supply mid-size functional beverage and supplement brands in Colombia, the Netherlands, and Brazil with consistent packaging output across all SKUs in their product portfolio.
Over ons
We are a specialist blow molding machine manufacturer with more than 20 years of continuous engineering investment in pharmaceutical and consumer goods packaging equipment. Our technical capability spans the full range from small-format single-cavity development machines through to high-speed six-cavity pharmaceutical production lines — and we have the patent portfolio to prove that each major design advance was earned through original engineering work rather than licensed from others. The HGA.ES-4C100 reflects the current state of our engineering art: a machine designed from the ground up for pharmaceutical producers who need both volume and process control in a single platform.
We ship complete packaged systems internationally — the blow molding machine, matched preform and blow tooling, auxiliary equipment, and a full technical documentation package that supports installation qualification in GMP-regulated facilities. Our application engineering team works with each client before order placement to verify that the machine specification matches the bottle geometry, production volume, and regulatory context. Clients in Colombia, South Korea, Australia, the Netherlands, and Brazil have successfully commissioned HGA.ES-4C100 systems under GMP conditions using our IQ/OQ documentation without requiring additional factory support during qualification — a measure of how thoroughly the commissioning process is documented before the machine leaves our production facility.
Whether you are evaluating blow molding machine manufacturers for a greenfield pharmaceutical packaging facility or looking to upgrade an existing production line from a lower-output machine, our team is available to discuss your project in detail and provide a technical recommendation based on your actual bottle specifications and production schedule.
Workshop
Auxiliary & Complementary Equipment
A four-cavity blow molding machine running at 4,600 bph places specific demands on its utility supply systems. We supply all auxiliary equipment as a single-source package, pre-configured to the HGA.ES-4C100 utility specification — eliminating the integration failures that commonly arise when compressed air, cooling water, and inspection systems are sourced separately and connected by a third party who was not involved in the machine design.
Oil-Free Air Compressor
The 4,000 ltr/min high-pressure blowing air demand of this machine requires a correctly sized oil-free compressor to ensure supply pressure stability at 35 kg/cm² throughout the production shift.
Temperatuurregelaar voor de matrijs
Cooling water stability at 8–12°C and 5–6 kg/cm² is critical for cycle-time consistency across all four blow cavities at 4,600 bph. A mold temperature controller holds the cooling setpoint to ±0.5°C regardless of ambient temperature swings, seasonal changes, or production load variation — the control precision that prevents the cavity-to-cavity temperature gradient from becoming a source of dimensional variation between bottles from different cavity positions in this automatic pet blowing machine.
Bottle Visual Inspection Machine
At 4,600 bph, manual sampling inspection cannot provide the statistical coverage that pharmaceutical GMP requires. An inline camera inspection system at the exit conveyor provides 100% screening for wall defects, neck-finish deviations, base integrity, and contamination in real time, automatically rejecting non-conforming bottles without interrupting production flow. This is how high-output blow molding machine lines maintain GMP compliance without proportional increases in quality inspection headcount.
Industrial Chiller & Compressed Air Package
We configure pre-matched chiller and compressed air utility packages specifically for the HGA.ES-4C100 flow rates and pressure requirements, delivered with connection documentation and commissioning support. Ordering utilities as a system package from the same source as the blow molding machine eliminates the undersized utility supply lines that are among the most common causes of underperformance during the initial production qualification phase for new pharmaceutical packaging installations.
Veelgestelde vragen
What are the steps involved in the two-stage blow molding process for producing 500 ml pharmaceutical supplement jars in a Colombian GMP facility?
De two stage blow molding process for pharmaceutical supplement jars runs as follows: preforms are injection-molded at the first station to the required neck finish and wall thickness specification; they are then cooled to a stable temperature and transferred to a preform carousel; the carousel moves them through a multi-zone near-infrared oven where each zone independently heats the preform to its programmed temperature; conditioned preforms then enter the four-cavity blow station where servo-controlled stretch rods extend to 350 mm while high-pressure air at 35 kg/cm² expands the preform against the cavity wall; blown bottles are cooled against the cavity surface, ejected, and transferred to the output conveyor for inline visual inspection. The entire cycle repeats 4,600 times per hour under PLC control with no operator intervention required between stations.
How does the HGA.ES-4C100 fully automatic blow moulding machine handle format changes between different neck finish sizes for a pharmaceutical contract packaging line in South Korea?
Format changes on the ES-4C100 Blow Molding Machine involve three steps: recalling the new recipe from the HMI (which restores all oven zone setpoints, stretch rod parameters, and blowing pressure ramp settings); swapping the preform injection mold and neck tooling components at the injection station; and swapping the blow mold cassettes at the blow station. For format changes within the same neck diameter — changing only the bottle body geometry — the injection station tooling remains in place and only the blow mold is exchanged, reducing changeover time to under 90 minutes in most cases.
Which types of blow molding machines are available for producing both narrow-neck syrup bottles and wide-mouth supplement jars on the same production line in Australia?
The HGA.ES-4C100 is one of the few blow molding machine formats that genuinely covers both requirements from a single machine frame. The 68 mm neck diameter ceiling accommodates wide-mouth supplement jar closures, while the 100 mm bottle mold-close distance supports the taller narrow-neck syrup bottle geometries that are standard in Australian pharmaceutical distribution. The key requirement for running both formats is maintaining separate validated recipes and tooling sets for each bottle specification, which the HMI recipe management system and standardized tooling change procedure on this machine are designed to support.
How does the energy consumption of a four-cavity automatic pet blowing machine compare to running two separate two-cavity machines at equivalent output for a pharmaceutical packaging facility in Colombia?
One HGA.ES-4C100 Blow Molding Machine running at 4,600 bph draws a steady-state electrical load of approximately 21 kW once oven zones stabilize. Two HGA.ES-2C114.3 units running simultaneously at 2,000 bph each would draw approximately 16 kW each — 32 kW total — to produce an equivalent 4,000 bph combined output, with the added complexity of two sets of auxiliary equipment, two operator positions, and two maintenance schedules. The single four-cavity blow molding machine therefore delivers both lower energy consumption per bottle and reduced operational complexity, which typically outweighs the lower initial tooling cost of the two-machine configuration once site running costs are factored in for a Colombian pharmaceutical facility.
Redacteur: PXY
