EP-HGA.ES-2C130 2 Cavities Medicine Bottle Blow Molding Machine
The EP-HGA.ES-2C130 occupies the large-format end of the two-cavity medicine bottle blow molding machine range, engineered specifically for pharmaceutical and healthcare manufacturers who need to produce containers above 1000 ml without moving to a more complex multi-cavity platform. Its 130 mm bottle mold-close distance and a maximum body diameter of 110 mm make it the natural fit for wide-shoulder pharmaceutical wash bottles, large oral liquid containers, antiseptic solution bottles, and certain clinical fluid packaging formats that narrower-bore machines simply cannot accommodate.
As a two-step blow molding machine, the process separates preform injection from blow molding entirely. Preforms produced to specification are loaded into the machine’s automated feed system, indexed through independently controlled infrared heating zones, then stretched axially and blown radially by high-pressure air at 26–35 kg/cm² into the cavity shape. The independence of the reheat stage from the injection process is the fundamental advantage of this two stage blow molding machine design for pharmaceutical applications: wall thickness distribution, biaxial orientation, and optical haze can each be tuned without reprocessing the preform batch. PET and PETG are the primary resin options, with the stretch-blow process delivering the material properties that meet international pharmacopoeial standards for container clarity, extractables, and mechanical resistance.
The machine’s electrical system draws a maximum heating power of 42.5 kW, settling to 8–13 kW in steady-state production. The dual air circuit runs low-pressure operation at 7 kg/cm² and high-pressure blowing between 26 and 35 kg/cm², consuming 600 ltr/min and 1000–1500 ltr/min respectively.
EP-HGA.ES-2C130 2 Cavities Medicine Bottle Blow Molding Machine
Model: EP-HGA.ES-2C130 | Series: Medicine Bottle Blow Molding Machine | Cavities: 2 | Max. Volume: 1500 ml
The EP-HGA.ES-2C130 is a fully automatic blow moulding machine engineered for high-volume pharmaceutical and medical packaging production, handling the largest container size in the two-cavity HGA.ES series. With a maximum container volume of 1500 ml, a wide 98 mm neck diameter range, and a production capacity of 1800 bottles per hour, this two-step blow molding machine is designed for oral liquid medicines, large-format antiseptic bottles, clinical wash containers, and premium cosmetic packaging. Its wide-body stretch geometry — with a 130 mm bottle mold-close distance and a stretching stroke of 350 mm — accommodates broad-shoulder pharmaceutical bottles that narrower-configured machines cannot handle. Markets across Colombia, Southeast Asia, the Middle East, and Europe actively specify this configuration for large-pack pharmaceutical lines where consistent wall thickness and optical clarity are non-negotiable production requirements.
Technical Specifications — HGA.ES-2C130
| Parameter | Unit | HGA.ES-2C130 |
|---|---|---|
| Molding | ||
| Clamping Stroke | mm | 160 |
| Mold-open Distance | mm | 360 |
| Mold-close Distance | mm | 200 |
| Stretching Stroke | mm | 350 |
| Preform Mold-open Distance | mm | 50 |
| Bottle Mold-close Distance | mm | 130 |
| Preform Holder | — | 60 |
| Cavities | — | 2 |
| Container | ||
| Max. Container Volume | ml | 1500 |
| Neck Diameter Range | mm | 98 |
| Max. Container Diameter | mm | 110 |
| Max. Container Height | mm | 250 |
| Theoretical Output | bph | 1800 |
| Electrical System | ||
| Max. Heating Power | kw | 42.5 |
| Heating Power (Normal Operation) | kw | 8–13 |
| Air System | ||
| Operating Pressure | kg/cm² | 7 |
| Low Pressure Air Consumption | ltr/min | 600 |
| Blowing Pressure | kg/cm² | 26–35 |
| High Pressure Air Consumption | ltr/min | 1000–1500 |
| Cooling Water | ||
| Operating Pressure | kg/cm² | 5–6 |
| Temperature | °C | 8–12 |
| Flow Rate | ltr/min | 30 |
| Machine Dimensions | ||
| Machine Size (L × W × H) | mm | 3600 × 1800 × 1990 |
| Machine Weight | kg | 3000 |
Machine Structure & Engineering Advantages
Where other blow molding machine configurations in the HGA.ES series are optimized for output rate, the EP-HGA.ES-2C130 is optimized for container geometry — specifically the wide-body, high-volume formats that the pharmaceutical and clinical supply industries depend on. Every mechanical system in this blow molding machine is scaled to the 1500 ml container challenge: wider clamping stroke, larger mold-open distance, and a 130 mm bottle mold-close dimension that gives designers the physical space to produce containers with meaningful shoulder width and stable base geometry.

Mold Engineering

Preform Injection Mold
- The gate insert is split into two matched components, securing true co-axial alignment during preform formation — a fundamental requirement for producing the uniform wall distribution that large-volume pharmaceutical containers demand.
- The cooling channel layout is calculated to extract heat evenly from the full preform body length, shortening the conditioning cycle while preserving dimensional stability before transfer to the blow station.
- All forming surfaces are produced from imported 2316 die steel, chosen for its combination of corrosion resistance and the hardness needed to sustain high-cycle pharmaceutical packaging production without progressive dimensional drift.
- Core plates, cavity plates, and supporting structural elements are manufactured in 420 stainless steel, providing corrosion resistance across varying production environments including high-humidity pharmaceutical cleanroom areas.
- Modular construction and standardized interchangeable fittings keep maintenance straightforward and spare part requirements predictable across production shifts.
- The mold architecture supports multiple preform configurations from a single base assembly, reducing tooling investment when pharmaceutical customers need to expand their container range without a complete mold change.

Blowing Mold
- Blow mold cavities are cut from premium tool-grade steel that balances surface hardness with the thermal conductivity needed for rapid heat extraction on large-volume container cycles in this blow molding machine.
- Each container profile is created and validated in 3D CAD software before machining begins, confirming that shoulder geometry, label panel area, and base stability meet the customer's packaging specification in the digital domain first.
- A broad range of pharmaceutical and clinical bottle profiles is available in our mold library, shortening development lead time for new container projects across wide-neck and large-volume formats.
- Cooling channels are precisely routed around the full cavity perimeter — especially critical on wide-body molds — to achieve the even temperature distribution that prevents warpage and maintains dimensional repeatability across continuous large-volume production.
- All metal components are finished on CNC multi-axis machining centers, producing the surface finish and dimensional accuracy that allow mold interchangeability without fitting adjustments between production changeovers.
Application Scenarios
The EP-HGA.ES-2C130 bottle blow molding machine is purpose-configured for the large-container segment of pharmaceutical, clinical, and personal care packaging. Its 1500 ml capacity, 110 mm maximum body diameter, and 98 mm neck diameter range cover formats that require a dedicated large-format blow molding machine — a specification class underserved by most standard pet blow molding machine configurations. This blow molding machine covers formats that narrower-bore machines simply cannot reach.

How to Choose the Right Blow Molding Machine for Large-Format Medicine Bottles
The EP-HGA.ES-2C130 is not the right blow molding machine for every pharmaceutical application — and understanding where it fits versus where a smaller or higher-cavity model better serves the production requirement is the starting point for any correct machine specification.
Container volume is the primary filter. If your maximum container size exceeds 1000 ml or your body diameter goes beyond 94 mm, the 2C130 becomes the logical candidate in the two-cavity ES range. Containers between 500 ml and 1000 ml with standard body proportions are often better served by the smaller-footprint models in the same series, which deliver higher bottles-per-hour figures for their cavity count. The 2C130's 1500 ml ceiling and 110 mm body diameter represent genuine geometric coverage that smaller-bore machines cannot provide.
Output rate versus container size. At 1800 bph for a two-cavity blow molding machine, this model is positioned for pharmaceutical manufacturers who prioritize container quality and format flexibility over maximum throughput. Large medicine bottle production rarely justifies six-cavity platforms because container volume itself limits downstream filling and packaging line speeds. A correctly sized two-cavity blow molding machine running at its designed output rate often outperforms an over-specified platform running at reduced efficiency to handle wide-body molds.
Utility infrastructure. At 3600 × 1800 × 1990 mm and 3000 kg, this blow molding machine requires more floor space and structural load capacity than the compact ES models. Pharmaceutical manufacturers in Colombia, Southeast Asia, and the Middle East planning a facility upgrade should verify both the floor plan and the electrical supply (42.5 kW peak) and cooling water circuit (30 ltr/min at 5–6 kg/cm²) against the machine's requirements before committing to this configuration.
Why Partner With Us
Over two decades of sustained engineering work in blow molding machine development have produced a team with deep practical knowledge of pharmaceutical packaging requirements — not just machine specifications. We have continuously refined our production systems, filed multiple national patents on key sub-systems, and built a client base that includes some of the most quality-sensitive brands in the food, beverage, cosmetics, and pharmaceutical industries.
Our specialized blow molding machines handle PET, PETG, PC, PCTG, and PP resins across applications from beverage to ophthalmic packaging. We are recognized as a leader in the high-end cosmetics, food, and pharmaceutical categories — sectors where machine reliability has direct regulatory consequences, not just commercial ones. Every blow molding machine we supply has completed a full-load production trial at our facility, with container measurements documented before shipment. Our after-sales team supports installations in Colombia, Southeast Asia, the Middle East, and Europe with remote diagnostics, local service coordination, and strategic spare parts guidance.
Partner Brands
Our installed blow molding machines produce containers used by some of the world's most demanding consumer and pharmaceutical brands, including Yibao, Haitian, Luhua, Walch, Blue Moon, Proya, Libai, Estée Lauder, Walmart, Da Senlin, and Shining Eye Drops — spanning water, edible oil, cosmetics, household care, and pharmaceutical packaging categories.

Recommended Auxiliary Equipment
A blow molding machine for large-format pharmaceutical container production performs to specification only when the surrounding utility equipment is correctly matched. We supply a complete auxiliary package alongside the machine, eliminating compatibility risk and giving pharmaceutical manufacturers a single accountable supplier for the entire system — from the blow molding machine itself through to cooling, air supply, and inline quality control.
Air Compressor
Oil-free high-pressure air compressors specifically matched to the blow molding machine's dual air circuit requirements (7 kg/cm² low-pressure and 26–35 kg/cm² blowing). Air purity is a GMP requirement for pharmaceutical-grade blow molding machine installations — oil contamination in the blowing air circuit directly affects container cleanliness.

Mold Temperature Controller
Precision mold temperature controllers maintain the blow molding machine mold at exact setpoints throughout production. On large-body molds, temperature uniformity has a greater effect on container geometry than on smaller formats — accurate mold temperature control directly reduces post-blow shrinkage variation and label-panel flatness deviation.

Bottle Visual Inspection Machine
Automated inline optical inspection systems catch wall thickness deviations, contamination, and neck finish nonconformities at the blow molding machine output before they reach downstream filling operations — essential for pharmaceutical container quality control under GMP frameworks.

Chiller & Compressor Package
Industrial water chillers maintaining the blow molding machine cooling circuit at 8–12 °C, bundled with oil-free air compressor supply. Combining both utility packages under a single supply relationship simplifies commissioning and eliminates inter-supplier compatibility disputes during installation.

About Us
Our blow molding machine engineering capability was built progressively over more than two decades, beginning with high-volume beverage PET bottle production and steadily extending into pharmaceutical, ophthalmic, and specialized clinical packaging — disciplines where the mechanical tolerances are tighter and the consequences of a sub-standard container can extend to patient safety outcomes. That progression required us to develop genuine in-house expertise in thermal management, stretch ratio control, and mold engineering for demanding container geometries, rather than adapting general-purpose blow molding machine platforms to pharmaceutical requirements.
Today our manufacturing operation produces fully automatic blow moulding machines, two-step blow molding machines, and injection stretch blow molding machines across a wide container range, supported by a complete auxiliary equipment offering and an engineering team with documented installation experience across Asia, Europe, the Middle East, and Latin America including Colombia. We design, manufacture, test, and support every blow molding machine from a single operation. Each blow molding machine goes through a full-load trial run before shipment, which means technical accountability stays with one team throughout the machine's operational life.
Our pharmaceutical blow molding machine clients include some of the largest generic pharmaceutical manufacturers and contract packagers in their respective markets. We understand the documentation, validation, and change control requirements that come with pharmaceutical packaging equipment purchases — and our technical teams support those processes from machine specification through IQ/OQ documentation to ongoing production support.
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Frequently Asked Questions
Q1. What makes a two-step blow molding machine the right choice for large-format pharmaceutical bottles above 1000 ml in the Colombian market?
A two-step blow molding machine separates the preform conditioning stage from the blowing stage entirely, giving operators full control over reheat temperature profiles independently of the injection process. For large-format pharmaceutical containers above 1000 ml — where wall thickness distribution errors are magnified by the greater stretch ratio — this independent thermal control produces significantly more consistent results than single-stage alternatives. Colombian pharmaceutical manufacturers benefit further from the two-step design's ability to stockpile preforms locally and adjust reheat profiles seasonally for ambient temperature variation, without disrupting the upstream preform production schedule.
Q2. How does this fully automatic blow moulding machine handle wide-neck pharmaceutical bottle formats that standard machines cannot accommodate?
The EP-HGA.ES-2C130's 130 mm bottle mold-close distance and 360 mm mold-open stroke are sized specifically to accommodate containers with body diameters up to 110 mm and neck diameters up to 98 mm. Standard blow molding machine configurations in the two-cavity segment typically cap body diameter at 65–94 mm, which excludes wide-mouth clinical wash bottles and large antiseptic containers. The extended clamping geometry of this fully automatic blow moulding machine eliminates that constraint without requiring a move to a larger multi-cavity platform that would be over-specified for 1500 ml container production.
Q3. Which resin is most suitable for producing 1500 ml pharmaceutical wash and antiseptic bottles on this injection blow molding machine?
For large-format antiseptic and clinical wash bottles, PETG is the preferred resin on this injection blow molding machine platform. PETG offers superior drop resistance compared to standard PET — a critical property for 1500 ml containers that are handled frequently in clinical environments — combined with good chemical resistance to the quaternary ammonium compounds and alcohol-based active ingredients common in hospital-grade antiseptics. PET remains the cost-effective choice for large oral liquid and syrup containers where drop resistance is a lower priority. Our application engineers specify the resin recommendation based on the individual API chemistry and container use scenario.
Q4. What utility infrastructure does a pharmaceutical facility in Southeast Asia need before installing this large-format blow molding machine?
The blow molding machine requires a low-pressure air supply at 7 kg/cm² consuming 600 ltr/min for machine operation, and a high-pressure oil-free air circuit at 26–35 kg/cm² consuming 1000–1500 ltr/min for blowing. A cooling water supply at 5–6 kg/cm², 8–12 °C, with 30 ltr/min flow is needed for the mold cooling circuit — a dedicated industrial chiller is standard on pharmaceutical installations. The electrical supply must support a 42.5 kW peak load. At 3600 × 1800 × 1990 mm and 3000 kg, the machine also requires an adequately reinforced floor and clear installation access. Our engineering team provides a full utility specification sheet and floor layout drawing with every machine quotation to support facility planning in Southeast Asia, Colombia, and other markets.
Editor: PXY




