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EP-HGA.ES-4C76 4 Cavities Medicine Bottle Blow Molding Machine

The EP-HGA.ES-4C76 occupies a distinctive position in the medicine bottle blow molding machine series: a four-cavity configuration that delivers pharmaceutical-grade output volume for standard-size containers without the dimensional trade-offs that come with six-cavity platforms optimized for smaller necks. At 4800 bottles per hour across four simultaneously operating blow cavities, this blow molding machine suits contract pharmaceutical manufacturers who need to run single-product high-volume lines. For dedicated pharmaceutical packaging operations, the blow molding machine delivers the output rate and container quality that strict production targets demand simultaneously. The 76 mm bottle mold-close distance accommodates containers up to 68 mm in body diameter and 240 mm in height — covering the majority of 100 ml to 700 ml pharmaceutical bottle formats in active production globally.

The machine operates on the two-step blow molding process, where preforms are produced independently and then reheated through multiple controlled infrared zones before being stretched and pressure-blown into the four-cavity mold. This two stage blow molding machine configuration keeps the preform thermal profile fully decoupled from the injection process, allowing operators to tune heating settings per cavity position and adjust for ambient conditions without disrupting upstream preform supply. The 40 kW maximum heating capacity of this blow molding machine draws down to 18 kW in steady-state production — an efficient power profile for the continuous 24-hour pharmaceutical production runs that high-output lines typically operate. PET and PETG are both fully supported, with PC and PCTG available upon mold specification.

Air supply runs through dual circuits: a low-pressure system at 7 kg/cm² consuming 800 ltr/min, and a high-pressure blowing circuit at 35 kg/cm² consuming 3900 ltr/min. The higher air consumption relative to the two-cavity models in the same series reflects the simultaneous blowing of four containers per cycle — each receiving a full blowing pressure charge for optimum molecular orientation and wall distribution. The cooling water circuit holds 8–12 °C with a 30 ltr/min flow rate, adequate for the 4-cavity cycle at 4800 bph, and the entire blow molding machine platform sits on a 3500 kg welded steel base within a footprint of 3290 × 1850 × 2260 mm.

EP-HGA.ES-4C76 4 Cavities Medicine Bottle Blow Molding Machine

Model: EP-HGA.ES-4C76  |  Series: Medicine Bottle Blow Molding Machine  |  Cavities: 4  |  Max. Volume: 700 ml

The EP-HGA.ES-4C76 is a high-throughput, fully automatic blow moulding machine built for pharmaceutical and medical packaging operations that demand consistent volume output without sacrificing container quality. Running four cavities in parallel, this blow molding machine reaches a theoretical output of 4800 bottles per hour — the highest single-model figure in the mid-range HGA.ES series — while maintaining the strict dimensional tolerances and surface clarity standards that pharmaceutical GMP production requires. Designed around a 76 mm bottle mold-close distance and a maximum container volume of 700 ml, the machine targets standard pharmaceutical bottles including oral liquid containers, wash solutions, toner bottles, and mid-size antiseptic packaging used across hospital supply chains in Colombia, Southeast Asia, the Middle East, and Europe.

4 Rongga
Quad-cavity high-output system
700 ml Max.
Oral liquid and wash bottle range
4800 bph
Highest mid-range ES series output
48 mm Neck
Standard pharmaceutical neck range
PET / PETG / PC
Multi-resin blow molding machine

Technical Specifications — HGA.ES-4C76

Parameter Satuan HGA.ES-4C76
Molding
Clamping Stroke mm 100
Mold-open Distance mm 300
Mold-close Distance mm 200
Stretching Stroke mm 350
Preform Mold-open Distance mm 50
Bottle Mold-close Distance mm 76
Preform Holder 96
Cavities 4
Container
Volume Kontainer Maksimum ml 700
Neck Diameter Range mm 48
Max. Container Diameter mm 68
Max. Container Height mm 240
Theoretical Output bph 4800
Electrical System
Max. Heating Power kw 40
Heating Power (Normal Operation) kw 18
Air System
Operating Pressure kg/cm² 7
Low Pressure Air Consumption ltr/min 800
Blowing Pressure kg/cm² 35
High Pressure Air Consumption ltr/min 3900
Cooling Water
Operating Pressure kg/cm² 5–6
Temperature °C 8–12
Flow Rate ltr/min 30
Machine Dimensions
Machine Size (L × W × H) mm 3290 × 1850 × 2260
Berat Mesin kg 3500

Engineering Advantages of the 4-Cavity Configuration

Moving from two cavities to four is not simply a doubling of output — it requires a blow molding machine platform recalibrated across every sub-system to deliver simultaneous, uniform blowing conditions to four separate container positions. The EP-HGA.ES-4C76 blow molding machine addresses this engineering requirement directly, producing 4800 bph with consistent per-cavity quality. A blow molding machine that achieves uniformity across all four cavities by design rather than by operator adjustment is a fundamentally more reliable pharmaceutical production platform.

⚙ Synchronized 4-Cavity Clamping
The blow molding machine's clamping system generates equal force across all four cavity positions simultaneously, maintaining identical mold-close distances at each station. Unequal clamping force in a multi-cavity blow molding machine is the primary cause of between-cavity weight variation — the engineering here eliminates that variable by design rather than relying on operator adjustment.
🌡 96-Position Preform Heating
With 96 preform holders in the reheat carousel, the blow molding machine maintains a deep buffer of conditioned preforms, allowing the four blow cavities to operate at their designed cycle rate without waiting on heating. This large preform buffer is one reason the 4C76 achieves its 4800 bph figure consistently rather than in burst cycles characteristic of under-buffered four-cavity systems on competing platforms.
💧 Uniform Mold Cooling
The cooling water circuit operates at 8–12 °C and 30 ltr/min, distributed across all four blow mold cavities through a balanced manifold. Even mold temperature distribution across all four positions is critical in a four-cavity blow molding machine: a 2 °C difference between cavity positions translates into measurable bottle weight variation that compounds over a production shift, directly affecting filling line performance downstream.
🔩 3500 kg Structural Platform
At 3500 kg, the blow molding machine base provides the rigidity needed when four simultaneous clamping and blowing events occur in rapid succession. Frame vibration in a four-cavity blow molding machine is four times more energetically demanding than in a two-cavity equivalent — the additional platform mass directly damps this vibration and protects mold alignment precision over the machine's full service life.
🤖 Multi-Cavity PLC Management
The blow molding machine PLC monitors and controls each of the four cavity positions independently, tracking temperature, pressure, and cycle timing for each station. This individual cavity monitoring capability means a single underperforming station can be identified and adjusted without stopping production — a practical advantage on continuous pharmaceutical packaging lines where unplanned downtime carries regulatory documentation implications.
💨 High-Volume Air Architecture
The blow molding machine's high-pressure air circuit delivers 3900 ltr/min at 35 kg/cm² — a volume requirement that underscores the engineering difference between this and smaller-cavity configurations. Each of the four cavities receives a full blowing charge per cycle, and the air circuit is sized to maintain that pressure consistently across the full 4800 bph production rate without pressure sag between cycles.

4-cavity blow molding machine customer installation

Mold Engineering

Preform Injection Mold

Preform Injection Mold

  • The gate system is constructed from two matched sections, ensuring true co-axial alignment throughout the preform formation cycle — the starting condition for achieving equal wall distribution across all four blow cavities in this blow molding machine.
  • Cooling channel geometry is designed for maximum heat extraction from each preform, shortening the conditioning cycle and sustaining the 96-position buffer that feeds four cavities at 4800 bph without thermal variation between positions.
  • All forming surfaces use imported 2316 die steel, selected for the combination of inherent corrosion resistance and mechanical hardness needed for sustained high-cycle pharmaceutical packaging production.
  • Core plates, cavity plates, and structural components are produced in 420 stainless steel, maintaining dimensional stability across variable humidity conditions including cleanroom-adjacent pharmaceutical environments.
  • The mold is designed for quick access and standardized interchangeable fittings, keeping scheduled maintenance intervals short and unplanned downtime predictable.
  • Advanced modular architecture allows a single mold base to accommodate multiple preform specifications, reducing tooling cost when expanding the product range on an established pharmaceutical line.

Blowing Mold

Blowing Mold

  • Four-cavity blow mold assemblies are machined from premium tool-grade steel, balancing surface hardness with thermal conductivity — both of which directly affect cycle time and container surface quality on a high-throughput blow molding machine.
  • Complete 3D CAD validation of every bottle geometry is completed before any machining begins, confirming that all four cavity positions will produce containers meeting the customer's dimensional specification without physical prototype iteration.
  • A broad library of pharmaceutical and personal care container profiles is available for selection, accelerating new product introduction timelines for pharmaceutical manufacturers who need to add SKUs to an existing blow molding machine installation.
  • Cooling channels are individually routed around each of the four cavity perimeters, ensuring thermal symmetry between positions that would otherwise produce cavity-to-cavity weight and geometry variation across a production shift.
  • All metal components are finished on CNC multi-axis machining centers to tolerances that ensure interchangeability between mold sets without manual fitting — a significant advantage for validated pharmaceutical packaging changeovers.

onestepblowmachine-products-show18 Medicine Bottle Blow Molding Machine

Skenario Aplikasi

The 4-cavity configuration of this bottle blow molding machine targets the volume segment between dedicated high-output lines and flexible two-cavity systems. The 700 ml ceiling, 68 mm body diameter, and 48 mm neck range position it squarely in the most commercially active zone of pharmaceutical bottle production — the standard oral liquid, wash, and antiseptic formats that move in the largest unit volumes across global pharmaceutical supply chains. No other blow molding machine configuration in the two-step series covers this combination of output rate and container size range as effectively.

💊 Oral Liquid Medicine Bottles
100–700 ml syrup, suspension, and oral solution containers are the core application for this blow molding machine. PETG amber and clear PET formulations are both supported, covering the UV-protection requirements of light-sensitive APIs and the cost-optimization needs of standard generic oral liquids.
🧴 Antiseptic & Disinfectant
Standard 250–700 ml antiseptic and hospital disinfectant containers account for a significant share of pharmaceutical plastic bottle output in Southeast Asia and Colombia. The fully automatic blow moulding machine format eliminates operator contact with the container neck during production, meeting the hygiene expectations of GMP packaging lines.
🧼 Clinical Wash & Scrub Solutions
Surgical scrub, wound wash, and clinical cleaning solutions require containers with PETG chemical resistance and a body geometry that allows complete drainage. The auto pet blowing machine process produces the uniform wall distribution that prevents channeling and dead-zone accumulation in clinical wash bottle formats.
🧪 Laboratory Reagent Bottles
Diagnostic laboratory reagent containers and clinical sample bottles share the dimensional profile of pharmaceutical oral liquid bottles and are frequently produced on the same four-cavity blow molding machine line. PETG compatibility with aqueous and mild organic solvents covers the majority of reagent packaging requirements.
💄 Cosmetic & Skin Care
Mid-size toner, lotion, and serum bottles — typically 150–500 ml — require the surface clarity and label-panel flatness that this pet blow molding machine process reliably delivers. High-output four-cavity production makes the platform economically viable for cosmetic brands with high monthly unit volumes.
🍼 Baby Care & Pediatric
PETG pediatric packaging — bath wash, infant supplement, and pediatric medicine bottles — benefits from the four-cavity blow molding machine's high throughput for high-volume baby care brands while maintaining the food-contact compliance and drop resistance that child-use containers require.

Medicine bottle blow molding machine production line

How to Choose the Right Blow Molding Machine Cavity Count for Pharmaceutical Bottles

The cavity count decision is often the most consequential machine selection choice a pharmaceutical manufacturer makes, because it determines both output capacity and quality management complexity for the life of the machine. The EP-HGA.ES-4C76 represents the four-cavity sweet spot for pharmaceutical oral liquid and wash bottle production at standard 100–700 ml container sizes — but it is not the automatic answer for every high-volume requirement.

When four cavities is the right choice. A four-cavity blow molding machine delivers the optimal balance of output rate and per-cavity quality management complexity for most pharmaceutical oral liquid lines. At 4800 bph, it satisfies the output requirements of mid-to-large generic pharmaceutical manufacturers without the tooling cost and quality monitoring complexity of a six-cavity platform. If your container is 100–700 ml with a body diameter under 68 mm and a neck below 48 mm, the 4C76 directly addresses that specification.

When to consider two cavities instead. If your production volume is below 2000 bottles per hour, or if your container geometry is atypical — very wide body, large neck, or tall-and-narrow profile — a two-cavity blow molding machine in the same HGA.ES series may achieve better per-bottle quality consistency at lower capital cost. Container geometry constraints that force one or two cavities to run suboptimally to accommodate the others will reduce the effective output advantage of the four-cavity configuration.

Utility and facility considerations. The four-cavity blow molding machine's high-pressure air consumption of 3900 ltr/min at 35 kg/cm² is the most critical utility requirement to verify before machine selection. Pharmaceutical facilities in Colombia, Southeast Asia, and the Middle East often run shared air infrastructure — verify that your existing or planned oil-free compressor capacity can sustain this demand without pressure drop across the full production shift before specifying this blow molding machine. Our blow molding machine application team provides utility specification sheets with every quotation.

Why Choose This Blow Molding Machine

Over two decades of focused blow molding machine development have produced not just a product range but a body of engineering knowledge that directly benefits every customer we supply. We continuously improve and patent key innovations across our blow molding machine systems — from multi-zone heating architectures to air circuit design and mold cooling optimization — and apply those improvements progressively across the range rather than treating them as proprietary advantages of individual models.

Our blow molding machines support PET, PETG, PC, PCTG, and PP resins across applications from ophthalmic eye drops to 1500 ml clinical wash containers. We are recognized in the pharmaceutical, cosmetics, and food industries as a supplier that understands both the mechanical and the regulatory requirements of packaging equipment — an important distinction for manufacturers who need a blow molding machine that supports GMP compliance rather than complicating it. Every machine leaves our facility after a documented full-load trial run with container measurement data provided to the customer.

✅ 20+ years pharmaceutical blow molding machine expertise
✅ Multi-cavity quality consistency by design, not adjustment
✅ PET / PETG / PC / PCTG / PP resin compatibility
✅ Full-load trial run with container data before shipment
✅ One-stop supply: machine, molds, and auxiliaries
✅ Service support in Colombia, Southeast Asia & Middle East

Partner Brands

Our blow molding machines run in production facilities serving some of the most demanding consumer and pharmaceutical brands globally, including Yibao, Haitian, Luhua, Walch, Blue Moon, Proya, Libai, Estée Lauder, Walmart, Da Senlin, and Shining Eye Drops. These client relationships reflect the trust that sustained blow molding machine performance builds in quality-sensitive industries.

Partner brands of our blow molding machine

Recommended Auxiliary Equipment

A four-cavity blow molding machine requires correctly specified auxiliary equipment to deliver its rated output consistently. The 3900 ltr/min high-pressure air demand and four-position mold cooling circuit are both more demanding than smaller-cavity configurations — mismatched auxiliaries on a four-cavity system directly reduce effective output and increase scrap rates. We supply a matched auxiliary package to eliminate these compatibility risks.

Air Compressor

Oil-free high-pressure compressors rated for the 3900 ltr/min demand of this four-cavity blow molding machine. Undersized compressor capacity is the single most common cause of output shortfall on four-cavity pharmaceutical blow molding machine installations — correct specification at the quotation stage prevents this entirely.

Air compressor for four-cavity blow molding machine

Pengontrol Suhu Cetakan

Precision mold temperature controllers for the blow molding machine four-cavity cooling circuit, maintaining equal setpoint temperatures at each position. Between-cavity temperature variation that would be tolerable on a two-cavity machine causes measurable weight deviation at four-cavity speeds — accurate temperature control is non-negotiable at 4800 bph.

Mold temperature controller

Bottle Visual Inspection Machine

Inline optical inspection at the blow molding machine output catches wall deviation, particle inclusions, and neck finish defects across all four container streams before they reach downstream filling — mandatory for GMP-compliant pharmaceutical packaging at 4800 bph production rates.

Bottle visual inspection machine

Chiller & Compressor Package

Industrial chillers maintaining the blow molding machine four-cavity cooling circuit at 8–12 °C, bundled with oil-free air compressor supply as a fully integrated and compatibility-verified utility package for pharmaceutical blow molding machine installations.

Auxiliary machinery for blow molding machine

Tentang Kami

Our blow molding machine development program began with high-volume beverage container production and progressively extended into pharmaceutical, ophthalmic, and specialized clinical packaging — industries where the tolerance for machine inconsistency is not measured in commercial rejects but in regulatory audit findings and product safety events. That progression shaped an engineering culture that treats multi-cavity quality uniformity as a fundamental design requirement, not a specification to be tuned in the field after installation.

The four-cavity blow molding machine platform represented by the EP-HGA.ES-4C76 reflects over two decades of accumulated knowledge about what makes a high-output pharmaceutical container production system reliable at commercial scale. We manufacture, test, and support every blow molding machine from a single operation, ensuring each blow molding machinehas one accountable technical contact for the machine, its molds, and its auxiliary equipment throughout the operational life of the installation. Our engineering and after-sales teams have hands-on experience supporting blow molding machine installations in Colombia, Southeast Asia, the Middle East, and Europe.

Our pharmaceutical blow molding machine clients range from regional generic manufacturers to global contract packaging organizations running multiple lines simultaneously. In each case, the requirements are the same: consistent cavity-to-cavity output, documented performance before shipment, and reliable after-sales support that does not require a factory visit for routine technical questions. We are structured to deliver all three.

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Pertanyaan yang Sering Diajukan

Q1. How does a four-cavity blow molding machine maintain consistent container quality across all cavities when producing pharmaceutical bottles at 4800 bph in a Colombian manufacturing facility?

Consistent quality across all four cavity positions requires three simultaneous conditions: equal clamping force at each station, equal preform temperature at each transfer position, and equal cooling rate at each mold cavity. The EP-HGA.ES-4C76 addresses each through its synchronized clamping system, the 96-position preform buffer that keeps heating zones in steady state, and the balanced four-position cooling manifold. For Colombian pharmaceutical manufacturers specifically, the machine's PLC allows individual cavity monitoring so that any drift from equal performance is identified and corrected before it generates measurable container variation in the batch record.

Q2. What are the differences between a two-stage blow molding machine and a single-stage machine when producing 700 ml pharmaceutical bottles in a high-volume pharmaceutical packaging plant?

In a single-stage blow molding machine, injection, conditioning, and blowing are linked in a single continuous sequence, which limits the ability to independently optimize each stage. In a two-stage blow molding machine, preforms are produced and stored independently before reheating and blowing, decoupling the thermal management of each stage. For 700 ml pharmaceutical bottles — where the stretch ratio is moderate and wall distribution requirements are strict — the two-stage approach allows reheat zone tuning that consistently produces better between-cavity wall uniformity than single-stage alternatives, particularly in high-volume four-cavity configurations where thermal consistency across positions is hardest to maintain.

Q3. How do I verify that my factory air supply infrastructure in the Middle East is adequate before installing this four-cavity injection blow molding machine?

The blow molding machine requires a high-pressure oil-free air supply capable of delivering 3900 ltr/min at 35 kg/cm² continuously. Before installation, measure your existing compressor's nominal capacity and actual sustained output under load — many facilities find their rated capacity drops 15–20% under continuous production conditions. Verify also that your distribution pipework can deliver this flow without pressure drop at the machine connection point, particularly in large Middle Eastern facilities where air lines run long distances from the compressor room. We provide a detailed utility specification sheet with every machine quotation and can advise on compressor sizing and pipework configuration for each installation site.

Q4. When should a pharmaceutical manufacturer choose a four-cavity blow molding machine over a six-cavity configuration for standard-size PET medicine bottles?

A four-cavity blow molding machine is generally preferable to six cavities when the container body diameter exceeds approximately 60 mm, when the production volume does not justify the additional mold and tooling cost of a six-cavity platform, or when the product mix includes multiple SKUs that each require their own validated mold set. A six-cavity blow molding machine delivers higher throughput but requires proportionally more rigorous between-cavity quality monitoring and larger tooling investment per format change. For a pharmaceutical manufacturer running a single high-volume SKU in the 100–700 ml range at a 48 mm neck, the four-cavity platform at 4800 bph typically represents the better total cost of ownership when tooling, maintenance, and quality management costs are included in the calculation alongside capital expenditure.

Editor: PXY